Isosorbide mononitrate 10mg immediate-release tablets, used to treat angina, are in limited supply until early September 2025, according to a medicine supply notification issued by the Department of Health and Social Care (DHSC).

Alternative strengths of isosorbide mononitrate immediate-release tablets remain available but cannot support increased demand.

Isosorbide mononitrate modified-release tablets and capsules (25mg, 40mg, 50mg and 60mg) are available and can support increased demand.

A copy of the medicine supply notification has been sent to all pharmacy NHS email addresses, along with actions required and supporting information.

The DHSC and NHS England/NHS Improvement Medicines Supply Tool on the Specialist Pharmacy Service (SPS) website provides up to date information on supply issues, including any changes to resupply dates. An NHS email address is required for access.

New shortages not listed on the SPS website can be reported using Community Pharmacy England’s shortage reporting tool.

This latest supply issue is one of many. Abidec Multivitamin drops, Diclofenac eye drops, loop diuretic tablets, and chronic pain patches have all been hit by stock shortages in the past few weeks.

Amiodarone 200mg tablets are also out of stock until early August 2025.

These shortages come after MPs found that medicine shortages were a ‘systematic threat’ to care, placing a huge burden on pharmacy teams and disrupting the delivery of treatment across England.